Seemingly a sympathomimetic drug with poor effect on Migraine relief. On latest update relevant data on breastfeeding was not found. Because a low excretion into breast milk Sumatriptan is a preferred drug. Other medication for Migraine relief like Triptans, Ibuprofen, Diclofenac and Ketorolate are more effective and at a lower risk for breastfeeding than Isometheptene.