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Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


Is it allowed to take 1,4-Dihydroxibenzene during lactation?
Is it safe for a nursing mother and a child?

Benzene derivative which is topically used with creams and solutions (2-4%) as a bleaching agent for several skin disorders associated to hyper-pigmentation. In industry it is used as photographic developer. TLV or threshold limit value which means maximum exposure limit for workers is 2 mg / m3 (Flickinger 1976). At latest update relevant published data were not found on excretion into breast milk. It is well absorbed through the skin, both when used as a therapeutic agent (Bucks 1998, Wester 1998, Westerhof 2005, Andersen 2010, Bozzo 2011) or industrial use (Barber 1995, McGregor 2007), however, a significant excretion into breastmilk is not likely for their lack of fat solubility. There is controversy and doubt about a possible mutagenic and carcinogenic effect (Kooyers 2004, FDA 2006, Levitt 2007, Andersen 2010), so it does not seem wise a chronic or continued use while breastfeeding. Do not apply it on the breast to prevent ingestion by the infant; otherwise, do it just after a meal and clean the nipple thoroughly with water before the next feed.Do not apply it over large areas or on long-term treatments to avoid an excessive systemic absorption.

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Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

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