1 1 1 1 1 1 1 1 1 1 Rating 3.80 (52 Votes)
Doctor

Recommendations made
pediatrician - Dr. Victоr Аbdоw
Rоckville, МD, USА.


woomen

Is it allowed to take Thiamazole during lactation?
Is it safe for a nursing mother and a child?

Excretion into breast milk is insignificant (Low 1979, Teller 1980).No adverse effects reported in breastfed infants (Rylance 1987). Plasma levels in those infants were shown to be low or undetectable (Azizi 2002-2003). Maternal daily dose as high as 20 - 30 mg has shown to be safe for the intant at short and long term with normal serum levels of T3, T4, TSH and psychomotor development that make routine blood test controls unnecessary (Lamberg 1984, Cooper 1987, Rylance 1987, Azizi 1996, 2000, 2002, 2003 y 2006, Mandel 2001, Bartalena 2005, Marx 2008, Inoue 2009, Glatstein 2009, Stagnaro 2011, Serrano 2014, Alexander 2017). It would be advisable to take the medication immediately after the breast feed to minimize infant exposition (Hudzik 2016). Given the risk of hepatic toxicity of propylthiouracil, methimazole is considered preferential treatment for hyperthyroidism, especially during breastfeeding (Karras 2009, 2010 and 2012, Azizi 2011, Serrano 2014, Hudzik 2016). American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding (AAP 2001)

doctor

woomen

Would you like to ask something else about Thiamazole ?
Ask your question through the form below.

Types of risk

VERY LOW RISK
It is allowed while breastfeeding. It is not dangerous for a baby. It is moderately safe. more...

LOW RISK PROBABLE
Possible presence in breast milk is allowed. Follow the doctor's recommendation. more...

HIGH RISK PROBABLE
An unsafe drug, it is necessary to assess the risks while taking. Use safer analogs. more...

VERY HIGH RISK
It is not recommended. You need to stop breastfeeding or choose a safe analog. more...

Scientific literature

The level of risk for breastfeeding is confirmed in these scientific publications:
  1. http://www.ncbi.nlm.nih.gov/pubmed/28056690
  2. http://online.liebertpub.com/doi/pdf/10.1089/thy.2016.0457
  3. http://www.ncbi.nlm.nih.gov/pubmed/25073822
  4. http://www.elsevier.es/en-revista-medicina-clinica-english-edition--462-pdf-S2387020615000376-S300
  5. http://www.ncbi.nlm.nih.gov/pubmed/24782995
  6. http://www.karger.com/Article/Pdf/336595
  7. http://www.ncbi.nlm.nih.gov/pubmed/24782994
  8. http://www.karger.com/Article/Pdf/336102
  9. http://www.ncbi.nlm.nih.gov/pubmed/21389085
  10. http://www.eje-online.org/content/164/6/871.full.pdf
  11. http://www.ncbi.nlm.nih.gov/pubmed/21851752
  12. http://www.ncbi.nlm.nih.gov/pubmed/21787128
  13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472679/pdf/thy.2011.0087.pdf
  14. http://www.ncbi.nlm.nih.gov/pubmed/21037541
  15. http://www.ncbi.nlm.nih.gov/pubmed/19602653
  16. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718594/pdf/0550701.pdf
  17. http://www.ncbi.nlm.nih.gov/pubmed/19675263
  18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726094/pdf/0550797.pdf
  19. http://www.ncbi.nlm.nih.gov/pubmed/20058397
  20. http://www.hormones.gr/pdf/Antithyroid%20drugs%20used%20in%20the%20treatment.pdf
  21. http://www.ncbi.nlm.nih.gov/pubmed/16418686
  22. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635531/pdf/nihms459198.pdf
  23. http://www.ncbi.nlm.nih.gov/pubmed/16682838
  24. http://www.ncbi.nlm.nih.gov/pubmed/16886586
  25. http://www.ncbi.nlm.nih.gov/pubmed/15952916
  26. http://www.tandfonline.com/doi/pdf/10.1517/14656566.6.6.851?needAccess=true
  27. http://www.ncbi.nlm.nih.gov/pubmed/12841536
  28. http://www.ncbi.nlm.nih.gov/pubmed/14714745
  29. http://www.ncbi.nlm.nih.gov/pubmed/12109618
  30. http://www.ncbi.nlm.nih.gov/pubmed/11533352
  31. http://pediatrics.aappublications.org/content/108/3/776.full.pdf
  32. http://www.ncbi.nlm.nih.gov/pubmed/11397822
  33. https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.86.6.7573
  34. http://www.ncbi.nlm.nih.gov/pubmed/10999814
  35. https://academic.oup.com/jcem/article-lookup/doi/10.1210/jcem.85.9.6810
  36. http://www.ncbi.nlm.nih.gov/pubmed/10205431
  37. http://www.ncbi.nlm.nih.gov/pubmed/8648549
  38. http://www.ncbi.nlm.nih.gov/pubmed/2882332
  39. http://www.ncbi.nlm.nih.gov/pubmed/2441601
  40. http://www.ncbi.nlm.nih.gov/pubmed/6546390
  41. http://www.ncbi.nlm.nih.gov/pubmed/6744638
  42. http://www.ncbi.nlm.nih.gov/pubmed/6897386
  43. http://www.ncbi.nlm.nih.gov/pubmed/6172233
  44. http://www.ncbi.nlm.nih.gov/pubmed/6158636
  45. http://www.ncbi.nlm.nih.gov/pubmed/91730

Add comment